Urology · real-world evidence · quality-of-care research
Departments of Urology, SUNY Downstate Health Sciences University & Maimonides Medical Center, Brooklyn, NY
A working portfolio. Each project below opens as a self-contained research hub — the question, how the cohort was built, every query, the figures, and the results, in one page.
When an older man starts androgen-deprivation therapy for prostate cancer, one moment carries two guideline duties: monitor his bones, and—if the cancer is already metastatic—intensify treatment. Examined together in one population, both duties fail at the same moment.
For twenty-two years low-dose vaginal estrogen carried the same boxed warning as high-dose systemic hormone therapy. The FDA removed it on November 11th, 2025. Nine months on either side of that date, prescribing rose — and it rose most in the women the warning had most deterred.
AUA guidelines require a post-void residual measurement to diagnose overactive bladder — which needs an in-office ultrasound, at odds with the telemedicine pathway the same guidelines endorse. One hundred women estimated their own residual before it was measured.
The Area Deprivation Index stands in for a patient's material circumstances across American health services research. It was built where distance means a car. Brooklyn is not that place — so does it measure what it claims to measure here?
Nocturia trials fixate on nightly void count. This project examines patient-defined treatment goals and how much nighttime urination patients are willing to tolerate — outcomes beyond the number.
Retzius-sparing robotic prostatectomy gives men better early continence, but preserving the anterior compartment may cost postoperative retention — and no study has examined retention as a primary outcome or identified who is at risk.
Urinary outcomes — incontinence and leakage — after HIFU and irreversible electroporation, the ablative options offered in place of whole-gland treatment.
Characterizing the incidence and demographics of ketamine-associated cystitis over the past decade — positioned to be the largest study of its kind to date.
A survey distributed to every urology residency in the country, measuring residents' knowledge of urogynecology and what shapes their perception of it — the pipeline question behind a subspecialty shortage.
Two procedures residents mostly learn by standing next to someone doing them: sacral neuromodulation lead placement and vaginal pessary fitting. Both were scripted, filmed and cut as teaching videos and submitted to the AUA's Core Curriculum.
In March 2022 the FDA warned that two widely used robotic vessel-sealing devices could fail to seal when too much tissue sits in the jaws. This study went to the FDA's own adverse-event database to ask what actually gets reported about them, and whether the two devices fail differently.
A study assistant built on a language model that answers Step 1 questions in a fixed high-yield structure and — the part that matters — points to the actual page in First Aid, AMBOSS or Rx Bricks rather than reproducing it.
Where the method came from: imaging and bench work at Emory and New York Medical College, beginning in high school through the STAR program.
The anterior insula has been studied in autism for years with conflicting results. Analyzing sex separately rather than adjusting it away, connectivity with the attention networks moved in opposite directions in autistic girls and autistic boys.
After status epilepticus a multi-part inflammatory response follows, driven partly by COX-2 signalling through the EP2 receptor. This work isolated the contribution of peripheral myeloid cells — the immune cells that arrive from outside the brain.
When brain-resident microglia are ablated, monocytes from the periphery move in and take up residence. Whether those engrafted cells behave like the microglia they replaced is the question the method was built to answer.
In the 5xFAD mouse, inflammatory gene induction during the prodromal stage — before plaques dominate the picture — differs between males and females.
Traumatic brain injury can set off epileptogenesis, and clinical data associate severe stress at the moment of injury with worse outcomes — but preclinical work had studied stress and injury only separately.
Around 200,000 oophorectomies are performed in the United States each year, each producing an abrupt loss of estradiol. What that loss — and its replacement — does to the dentate gyrus was the question of my first study.